General and clinical pathology

About the department:
Pathology is a clinico-morphological discipline studying disease processes. It requires a narrow collaboration between different clinics and constitutes the point of intersection between fundamental medical sciences and clinical practice. The Department of general and clinical pathology is an important diagnostic unit and consists of a histopathology laboratory and two autopsy rooms, with highly trained specialists and a full complement of highly specialized equipment and methodology.

The general and clinical pathology department performs diagnostics, examination and analysis and elaborates strategies of therapeutic conduct as well as postmortem examination.

Our routine practice includes the following approaches.

Fully automated cycle and processing of biopsy samples – tissue samples from various doubtful or pathologically altered areas, organ structures or whole surgically removed organs, followed by a large spectrum of histological examinations:

Cytological examinations – morphologic evaluation of biological fluids and the cellular elements within, obtained through punctures, effusions, lavages, aspirates and other methods.

Emergency intraoperative diagnostics (frozen section procedure) consisting in freezing tissues and performing histological sections during an operative intervention in order to determine the nature of the disease process; the procedure has a decisive incidence on the volume of the surgical operation.

Immunohistochemical analysis – a highly specialized study of histological or cytological preparations in order to distinguish different types of tumors, tumor-like conditions and many non-tumor processes. This method allows to determine predictive factors, histogenesis of tumors, typology of tumors, marks defining the biological behavior of the tumor (the disease process), as well as to establish a strategy of therapeutic conduct.

Diagnostics of tumors with uncertain primary focus.

Consultation of ready histology preparations and paraffin blocks from the disease process, with the possibility for a complete study and the presentation of the patient before the multidisciplinary tumor board.

Postmortem study of the cadaver and the pathologic processes within, using the macroscopic examination methods, followed by an analysis using the histopathological methods described above.