Клиническое развитие,
снованное на научном опыте
и усовершенствованных методологиях
снованное на научном опыте
и усовершенствованных методологиях
Клинические испытания
Болгарский институт сердца в сотрудничестве с фармацевтической промышленностью активно участвует в клинических разработках, используя анализ данных здравоохранения, инновационные медицинские технологии, передовые методики и научные знания.
Все клинические исследования проводятся в соответствии с требованиями европейского и болгарского законодательства и в строгом соответствии с правилами надлежащей клинической практики.
В ноябре 2022 года препарат «Сердце и мозг» успешно прошел проверку, проведенную Управлением по контролю за продуктами и лекарствами США (FDA). Полученная оценка гласит: «Без существенных замечаний, с признанием открытости клинического центра».
| Area | Research Centre | Principal Investigator | Condition or disease | Completed | Ongoing |
| Cardiology | Cardiology Hospital Pleven | Dr Valentin Hristov | Type2 Diabetes; Dyslipidemia | X | |
| Cardiology | Cardiology Hospital Pleven | Dr Valentin Hristov | Cardiovascular Disease | X | |
| Cardiology | Cardiology Hospital Pleven | Dr Valentin Hristov | Myocardial Infarction | X | |
| Cardiology | Cardiology Hospital Pleven | Dr Valentin Hristov | Atrial Fibrillation | X | |
| Cardiology | Cardiology Hospital Varna | Prof. Nikolay Penkov | Acute Coronary Syndrome | X | |
| Cardiology | Cardiology Hospital Varna | Prof. Nikolay Penkov | High cholesterol | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | COVID-19 | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | COVID-19 | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | COVID-19 | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | COVID-19 | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | Hypertension | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | Hypertension | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | Atherosclerotic Cardiovascular Disease | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | Heart Failure With Preserved Ejection Fraction | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | Atherosclerotic Cardiovascular Disease | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | Cardiovascular Risk, Chronic Kidney Disease, Inflammation | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | Myocardial Infarction | X | |
| Cardiology | Heart and Brain Pleven | Prof. Iana Simova | Cardiovascular Disease | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Focal seizures in adult subjects with drug-resistant focal epilepsy | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Focal seizures in adult subjects with drug-resistant focal epilepsy | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Relapsing-remitting form of multiple sclerosis | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Relapsing forms of multiple sclerosis | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Migraine | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Parkinson’s disease | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | COVID-19 | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Parkinson’s disease | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Progressive multiple sclerosis | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Relapsing-remitting form of multiple sclerosis | X | |
| Neurology | Heart and Brain Pleven | Prof. Plamen Bozhinov | Stereotyped, prolonged seizures | X | |
| Oncology | Heart and Brain Pleven | Assoc. Prof. Natalia Chilingirova | Squamous Cell Non Small Cell Lung Cancer; Prostate Cancer; Metastatic Cutaneous Melanoma; Colorectal Cancer; Advanced Cancer; Solid Tumor, Adult | X | |
| Oncology | Heart and Brain Pleven | Assoc. Prof. Natalia Chilingirova | Cutaneous Squamous Cell; Carcinoma Advanced Cutaneous Squamous Cell Carcinoma; Metastatic Cutaneous Squamous Cell Carcinoma | X | |
| Oncology | Heart and Brain Pleven | Assoc. Prof. Natalia Chilingirova | ER-Positive HER2-Negative Breast Cancer | X | |
| Oncology | Heart and Brain Pleven | Assoc. Prof. Natalia Chilingirova | Breast Neoplasms; Breast Cancer; HER2-positive Early Breast Cancer | X | |
| Oncology | Heart and Brain Pleven | Assoc. Prof. Natalia Chilingirova | Locally Advanced or Metastatic Unresectable Urothelial Cancer | X | |
| Oncology | Heart and Brain Pleven | Assoc. Prof. Natalia Chilingirova | Carcinoma, Non-Small-Cell Lung | X | |
| Oncology | Heart and Brain Pleven | Assoc. Prof. Natalia Chilingirova | Hormone-Sensitive Prostate Cancer | X | |
| Oncology | Heart and Brain Pleven | Assoc. Prof. Natalia Chilingirova | Non-Small Cell Lung Cancer | X | |
| Cardiology | Heart and Brain Burgas | Assoc. Prof. Lilyana Mircheva | Prevention of Stroke or Systemic Embolism; Atrial Fibrillation | X | |
| Neurology (Medical Imaging Department ) | Heart and Brain Burgas | Prof. Ivan Dimitrov (with Ass. Prof. Lachezar Manchev) | Multiple Sclerosis | X |
Status: March 2023; the list is not exhaustive.